Race Labeling Of Non Whites From Clinical Trials - 1656 Words

Moreover, Bidil race labeling might actually have undermined the broader goal of increasing racial minorities’ participation in clinical trials (Winickoff and Obasogie, 2008). For instance, by specifying African Americans as the only beneficiaries of BiDil, the same idea could be applied for a special efficacy drug for Whites, â€Å"the largest and most lucrative population segment of the United States† (Winickoff and Obasogie,2008). This logic could be used to justify the exclusion of non-Whites from clinical trials. This seems to be what happened in 2006 when Schering-Plough decided to exclude African Americans from the Phase 2 trial of SCH 503034, an investigational hepatitis C protease inhibitor. â€Å"Even though African Americans have the highest hepatitis C prevalence of any racial group in the United States, the company excluded this population not for any safety rationale but to boost efficacy numbers† (Winickoff and Obasogie,2008). BiDil, as a race-spe cific medicine also encourages the trend for other pharmaceutical companies to try and come up with other drugs in order to copy Bidil marketing success. The role of law as a player in the emergence of Bidil as an ethnic drug began in the 1980s, around the same time as the initiation of V-HeFT I (Kahn,2005). Two legislations signed by President Carter would encourage interactions between industry and academic researchers and inevitably make it easier for Bidil to emerge as an ethnic drug. The first, the Stevenson- WydlerShow MoreRelatedQuestions On Drug Information Services3242 Words   |  13 Pagesclotrimazole lozenges, nystatin suspension, or oral fluconazole.1 Posaconazole, compared to fluconazole as prophylaxis against fungal infections in hematopoietic stem cell transplant patients with graft-versus-host disease, demonstrated similar rates of clinical failure to fluconazole but was superior in preventing invasive aspergillus infections and in preventing death. There was no difference in rate of candidiasis infection comparing fluconazole and posaconazole prophylaxis within the study.5 For oropharyngealRead MoreAbnormal Psychology. Classification and Assessment of Abnormal Behavior20707 Words   |  83 Pages3 CHAPTER Classification and Assessment of Abnormal Behavior CHAPTER OUTLINE HOW ARE ABNORMAL BEHAVIOR PATTERNS METHODS OF ASSESSMENT 80–99 CLASSIFIED? 70–77 The Clinical Interview The DSM and Models of Abnormal Behavior Computerized Interviews Psychological Tests STANDARDS OF ASSESSMENT 77–80 Neuropsychological Assessment Reliability Behavioral Assessment Validity Cognitive Assessment Physiological Measurement SOCIOCULTURAL AND ETHNIC FACTORS IN ASSESSMENT 99–100 SUMMING UP 100–101 TRead MoreHiv/Aids in Nigeria6960 Words   |  28 PagesAdult HIV prevalence increased from 1.8% in 1991 to 5.8% in 2001. This infection rate, although lower than that of neighboring African countries should be considered in the context of Nigeria’s relatively among population of approximately 117 million, the joint United Nations programme on HIV/AIDS (UNAIDS) by the end of 2001. HIV prevalence among women attending continental clinic in 1999 rose from less 1% to 21%. Among sex workers in Lagos. HIV prevalence rose from 2% in 1988-89 to 12% in 1990-91Read MoreHemp Cultivation in China42289 Words   |  170 Pagesoverlap these concerns. Examples of these efforts include the following. ---Textile Forum magazine, published by the European Textiles Network, devoted most of their June issue to hemp and derived much of their information from the IHA. If you haven t seen it, you can order a copy from the IHA bookstore. It’s a beautifully done issue, with nice color plates. ---The IHA has been invited to join the FAO hemp/flax network and our journal received a favorable review in the June 1995 issue of its periodicalRead MoreEssay about The Results of Children in Fatherless Homes16087 Words   |  65 Pagestwo-parent families to have emotional and behavioral problems. They are also more likely to drop out of high school, to get pregnant as teenagers, to abuse drugs, and to be in trouble with the law. Compared with children in intact families, children from disrupted families are at a much higher risk for physical or sexual abuse. Contrary to popular belief, many children do not bounce back after divorce or remarriage. Difficulties that are associated with family breakup often persist into adulthoodRead MoreGsk Annual Report 2010135604 Words   |  543 Pagesreports Remuneration policy Director terms and conditions Director and Senior Management remuneration Directors’ interests Directors’ interests in contracts 08 10 12 14 18 19 20 21 22 29 34 41 47 53 Business review This discusses our ï ¬ nancial and non-ï ¬ nancial activities, resources, development and performance during 2010 and outlines the factors, including the trends and the principal risks and uncertainties, which are likely to affect future development. Governance and remuneration This discussesRead MoreCissp Study Guide67657 Words   |  271 Pagesstatement of roles and responsibilities C. statement of applicability and compliance requirements. D. statement of performance of characteristics and requirements. Answer: D Explanation: Policies are considered the first and highest level of documentation, from which the lower level elements of standards, procedures, and guidelines flow. This order , however, does not mean that policies are more important than the lower elements. These higher-level policies, which are the more general policies and statementsRead MoreBrand Building Blocks96400 Words   |  386 Pagesare under the control of the organization, cause many of the formidable problems facing brand builders today. 1. Pressure To Compete On Price There are enormous pressures on nearly all firms to engage in price competition. In all industries from computers to cars to frozen dinners to airlines to soft drinks, price competition is at center stage, driven by the power of strong retailers, value-sensitive customers, reduced category growth, and overcapacity (often caused by new entrants and byRead More_x000C_Introduction to Statistics and Data Analysis355457 Words   |  1422 Pageswritten permission of the publisher. Thomson Higher Education 10 Davis Drive Belmont, CA 94002-3098 USA For more information about our products, contact us at: Thomson Learning Academic Resource Center 1-800-423-0563 For permission to use material from this text or product, submit a request online at http://www.thomsonrights.com. Any additional questions about permissions can be submitted by e-mail to thomsonrights@thomson.com. Printed in the United States of America 1 2 3 4 5 6 7 11 10 09 08Read MoreChange Management49917 Words   |  200 Pagesit is called reactive change. However, proactive change is initiated by the management on its own to enhance the organizational effectiveness. The change is one of the most critical aspects of effective management. It is the coping process of moving from the present state to a desired state that individuals, 1 MBA –H4010 Organisational Development And Change groups and organizations undertake in response to various internal and external factors that alter current realities. Survival of